Have you ever experienced chest pain? It may be angina!
Angina pectoris is a primary symptom of coronary artery disease (CAD), which can lead to myocardial infarction and a heart attack if not treated. But don’t worry; with the advances in healthcare and the medicines available in the pharmacy nearby, you just need to get timely and proper treatment. According to the World Health Organization, over 7 million people die of coronary artery disease (ischemic heart disease) every year.
The pain of angina feels like a heart attack, but it is a warning sign. Pain may extend into the arms, back of the neck, back, upper abdomen or jaw. Angina occurs due to the narrowing of the blood vessels, which supply blood to the heart. Thus, heart muscles do not get enough blood and oxygen.
Management of Angina
The management of Angina aims to reduce pain and decrease the risk of a heart attack. General management of angina includes necessary lifestyle modifications like quitting alcohol and smoking, including regular exercise to control weight and a balanced diet (avoiding large meals). Medicines, along with lifestyle changes, can effectively be used in the management of angina pectoris. The various medicines prescribed in the management of angina are nitrates, calcium channel blockers, potassium channel openers, beta blockers, anticoagulants, and oral antiplatelet medications.
Among all these classes, potassium channel openers such as Nicorandil are the most effective antianginal drugs, even in patients who do not respond to nitrates and antianginal combination therapy. It reduces the intensity of angina attacks by relaxing the blood vessels. It is used in the management of various ischemic heart diseases, including angina, myocardial infarction, and heart failure. Let’s understand how Nicorandil is useful in the management of Angina.
Nicorandil
Nicorandil is an effective and well-tolerated treatment for various types of angina pectoris. It is a drug with both potassium channel-activating properties and nitrate-like properties. It acts by balancing coronary and peripheral vasodilatation and reduces both preload and afterload.
Besides, Nicorandil helps increase the availability of oxygen to the tissues, lowering the BP. Thus, nicorandil is a valuable addition to antianginal drugs due to its good tolerability and less serious side effects. Dr best Pharmaceuticals Pvt Ltd provides DRNIC (Nicorandil 5 mg) at 80% discount and ensures that treatment should not suffer due to high prices.
How does it work?
Nicorandil reduces the angina by widening the blood vessels that supply blood to the heart and, hence, increasing the blood flow. It is an adenosine triphosphate (ATP) – sensitive potassium (KATP) channel agonist with nitrate-like properties.
The KATP channel opening reduces cardiac afterload by producing a sustained dilating action on both arterial and coronary vasculature (coronary artery conductance and resistance vessels) and increasing coronary blood flow. It improves the blood and oxygen supply of your heart muscles, reducing the workload on the heart.
Uses of Nicorandil
It is used in patients who cannot take other cardiovascular drugs, such as beta-blockers and calcium channel blockers. Used in the prevention and long term treatment of chronic angina pectorisReduces the risk of acute coronary syndromes like Myocardial infarction and CHD (Congestive Heart Disorder)Taking Nicorandil regularly can reduce the risk of an ischemic heart condition.
Dosage of Nicorandil
It is well tolerated with a twice-a-day dosing schedule and is available in the form of tablets. The dose is initiated with 10 mg and may be increased up to 40 mg if required. If you often get headaches, you may be given a smaller starting dose of 5 mg, which can be increased afterwards.
Side effects of Nicorandil
Nicorandil is generally safe and well tolerated, but the common side effects include headache, nausea, vomiting, weakness, hypotension (at very high doses), abdominal pain, dizziness and mouth ulcers.
General Warnings
- Do not take Nicorandil without consulting physician.
- In the event of any severe or unusual effects, consult the doctor immediately.
- Avoid this medicine if you are suffering from reduced blood flow, low systolic blood pressure, acute left ventricular failure, or acute pulmonary edema. Due to the risk of severe hypotension, the use of
- Nicorandil and phosphodiesterase 5 inhibitors (sildenafil, tadalafil) are contradictory. It is not recommended for use during pregnancy or breastfeeding.
We hope now you are well aware of the importance of Nicorandil in Angina Pectoris.
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Conclusion
In conclusion, by functioning as a relaxant and potassium channel opener, Nicorandil is a strong anti-anginal drug that relieves angina-related chest discomfort. Its double effect reduces symptoms and promotes general cardiac health by increasing blood flow to the heart.
Nicorandil, which is accessible from neighbourhood pharmacies, is a useful choice for those who are managing angina. To guarantee safety and efficacy, it is imperative to use this drug under medical supervision and to follow recommended doses. It is always advisable to speak with your doctor before beginning a new pharmaceutical regimen.
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