Nicorandil: Anti-Anginal Drug Available in Pharmacy Nearby


Have you ever experienced chest pain?
It may be angina!

Angina Pectoris is a primary symptom of coronary artery disease(CAD) which can lead to myocardial infarction and heart attack if not treated. But don’t worry, with the advances in healthcare and the medicines available in the pharmacy nearby, you just need to get timely and proper treatment. According to the World Health Organization, over 7 million people die of coronary artery disease (Ischemic heart disease) every year. The pain of Angina feels like a heart attack, but, it is a warning sign. Pain may extend into the arms, back of the neck, back, upper abdomen or jaw. Angina occurs due to the narrowing of the blood vessels which supply blood to the heart. Thus heart muscles do not get enough blood and oxygen.

Management of Angina
The management of Angina aims to reduce pain and decrease the risk of a heart attack. General management of angina includes necessary lifestyle modifications like quitting alcohol and smoking, including regular exercise to control weight and a balanced diet (avoiding large meals). Medicines, along with lifestyle changes, can effectively be used in the management of angina pectoris. The various medicines prescribed in the management of Angina are nitrates, calcium channel blockers, potassium channel openers, beta blockers, anticoagulants, oral antiplatelet medications. Among all these classes, potassium channel openers such as Nicorandil is the most effective antianginal drug even in patients who do not respond to the nitrates and antianginal combination therapy. It reduces the intensity of angina attacks by relaxing the blood vessels. It is used in the management of various ischemic heart disease including angina, myocardial infarction and heart failure. Let’s understand how Nicorandil is useful in the management of Angina.

Nicorandil is an effective and well-tolerated treatment for various types of angina pectoris. It is a drug having both potassium channel activating properties and nitrate like properties. It acts by balancing coronary and peripheral vasodilatation and reduces both preload and afterload. Besides, Nicorandil helps to increase the availability of oxygen to the tissues lowering the BP. Thus, nicorandil is a valuable addition to antianginal drugs due to its good tolerability and less serious side effects. Dr best Pharmaceuticals Pvt Ltd provides DRNIC (Nicorandil 5 mg) at 80% discount and ensures that treatment should not suffer due to high prices.

How does it work?
Nicorandil reduces the Angina by widening the blood vessels which supply blood to the heart and hence, increases the blood flow. It is an adenosine triphosphate (ATP) – sensitive potassium (KATP) channel agonist with nitrate-like properties. The KATP channel opening reduces cardiac afterload by producing a sustained dilating action on both arterial and coronary vasculature (coronary artery conductance and resistance vessels) and increasing coronary blood flow. It improves the blood and oxygen supply of your heart muscles to reduce the workload on the heart.

Uses of Nicorandil
It is used in patients who cannot take other cardiovascular drugs such as beta-blockers and calcium channel blockers. Used in the prevention and long term treatment of chronic angina pectorisReduces the risk of acute coronary syndromes like Myocardial infarction and CHD (Congestive Heart Disorder)Taking Nicorandil regularly can reduce the risk of an ischemic heart condition.

Dosage of Nicorandil
It is well tolerated with a twice in a day dosing schedule and available in the form of tablets. The dose is initiated with 10 mg and may be increased up to 40 mg if required. If you often get headaches, you may be given a smaller starting dose of 5 mg, which can be increased afterwards.

Side effects of Nicorandil
Nicorandil is generally safe and well tolerated, but the common side effects include headache, nausea, vomiting, weakness, hypotension (at very high doses), abdominal pain, dizziness and mouth ulcers.

General Warnings
Do not take Nicorandil without consulting physician.
In case of any severe, unusual effects consult the doctor immediately.
Avoid this medicine if you are suffering from reduced blood flow, low systolic blood pressure, acute left ventricular failure and acute pulmonary oedema. Due to the risk of severe hypotension, the use of Nicorandil and Phosphodiesterase 5 inhibitors (sildenafil, tadalafil) is contradicted. It is not recommended to use during pregnancy and breastfeeding.
We hope now you are well aware of the importance of Nicorandil in Angina Pectoris.

You can easily get the prescribed dose of DRNIC (Nicorandil) from Dr Best Pharmaceuticals Pvt Ltd. All our medicines are remarkably good in quality and cost effective as well.

Dr Best Pharmaceutical Pvt Ltd strives to decrease the burden of expensive medicines on the patients.
Our online pharmacy 24 hours is consistently working to provide medicines of major therapeutic classes such as cardiovascular drugs, antihypertensives, antihyperlipidemic drugs, antibiotics, antidiabetics, analgesics, vitamins and many more products at 80% lesser price for the benefit of the Indian population. We are offering these online medicines with a maximum discount so that any patient should not suffer from the high cost of cardiovascular drugs. Go for online medicine with Dr Best Pharmaceuticals Pvt Ltd and save huge with the online offers.

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